J. Environ. Chlorpheniramine and brompheniramine, antihistamines that help relieve allergies. 2019;38:762774. https://forum.propeciahelp.com/t/my-story-yes-it-was-messy-and-yes-i-am-fine-now/5456. Do you have cloudy urine after an orgasm? Li X, Guo Y, Lu Y, Li H, Yan S, Li H, Li Y. Transl Androl Urol. This content does not have an Arabic version. At higher doses, finasteride (Proscar) can also treat benign prostatic hyperplasia (BPH). Post Finasteride Syndrome Diviccaro S, Giatti S, Cioffi L, Falvo E, Herian M, Caruso D, Melcangi RC. There was this guy on propecia help called JustQuitDut who was a complete psycho, who thought that taking TRT with estrogen blockers would somehow solve it. Do you have diabetes or any other chronic health problems? Melcangi RC, Caruso D, Abbiati F, Giatti S, Calabrese D, Piazza F, Cavaletti G. J Sex Med. Epub 2022 Feb 3. Partin AW, et al., eds. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). I had a case of PFS that was a severe as it gets. In addition, it has been also reported that persistent side effects may occur in some AGA patients. I do not think we have an answer to that question one way or the other. Should I be concerned? I could stand to lose about 30 pounds. 2015 Sep;16(3):177-98. doi: 10.1007/s11154-015-9319-y. Hum. Will medications help me ejaculate normally? The drug has a very short half life in the bode, but the $1,000,000 question is whether there a a long-term alteration in DHT production and/or effectiveness. Talking with a counselor might help. Plus, get a FREE copy of the Best Diets for Cognitive Fitness. WebPost-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested in clinical symptoms that develop and persist in patients during and/or after discontinuing finasteride treatment in men with pattern hair loss (androgenetic alopecia) or Ohl DA, et al. I was on TRT when I got PFS. Maybe if theyre lucky in 10 years. For details, see text., Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. In some people with PFS, DHT might be normal, but testosterone and cortisol low and estrogen and prolactin high. there are many options including peptides, and HCG as well as clomid/arimidex. The dosage needs to be low and steady, do not increase or add a day thinking more is better. Ive seen many others who give their opinion but are banned as a result. After a few days I starting liking women again and became sexually from frustrated. The drug reduces a testosterone-related hormone in certain tissues, including skin and the prostate gland. WebHow to Correct Post Finasteride Syndrome Minimize Stressors. Crazy. I recovered and I hope all of you suffering from PFS recover too. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). FOIA I'll be interested to see if this has any effects on my weight loss endeavors. When seeing your doctor for dry ejaculation the primary sign of retrograde ejaculation some basic questions to ask your doctor include: If you're trying to get your female partner pregnant, you might also want to ask: In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask additional questions during your appointment. decreased libido * (sex drive) erectile dysfunction *. Jefferys A, et al. This condition, termed post-finasteride syndrome (PFS) is characterized by sexual side effects (i.e., low libido, erectile dysfunction, decreased arousal and difficulty in achieving orgasm), depression, anxiety and cognitive complaints that are still present despite drug withdrawal. "I had a case of PFS that was a severe as it gets. i am so desperate.. i am a female.. i need my hair back.. but o reallu cannot undergoo all this syntomps ( i gained 20 kg on fina and dutasterde.. no muscle stranght anymore.. no way to lose weight.. i really can' t tell a lot about mental and neurological condition.. but II am so depressed too.. but probably because I am bald and fat there must be a way to take fina without sides.. there must be a way..). I have had a recent report of a man who went on Human Growth Hormone and reversed his post finasteride syndrome sexual dysfunction. For details, see text. Hello, some finasteride users have reported the reversal of post-finasteride syndrome using HCG as therapy. Preparing a list of questions before your appointment can help you make the most of your time together. To be honest, I think for the most part these recoveries werent PFS but rather hormonal imbalances. Arimidex 0.5mg-3mg a day as needed (keep this dose around 1mg a day, too high and you will have low estrogen, torem may prevent you from needing it, everyone is different, I may not need it anymore, I recommend taking it only as needed, Torem 60mg a day (new drug instead of hcg that is an estrogen blocker and being tested as a treatment for androgen insensitivity), DHEA 50mg 1-2X a day (sometimes 2 X if I feel I need a mood boost), Calcium D Glucarate 1500mg (as many times a day as I remember, about 3X is good), Reservatrol (whatever dose a day, its an extra), https://forum.propeciahelp.com/t/final-protocol-100-pfs-reversal-with-dht-therapy-lastpost/7845/2147. Feeling low-grade depression constantly. I'm not going to go into the entire history of what post finasteride syndrome is, and I assume many of you looking into buying Tribulus know exactly what it is. Palliative care frightens some people: Heres how it helps, Parents don't always realize that their teen is suicidal. Ive been doing this for over 2 years and have ZERO sexual side effects from the drug. Or at the very least allow people to post ideas. https://www.isarms.com/forums/threads/post-finasteride-syndrome.18175/. More than a primer on prostate conditions, this Special Health Report, the Annual Report on Prostate Diseases, includes roundtable discussions with experts at the forefront of prostate research, interviews with men about their treatment decisions, and the latest thinking on complementary therapies. But it is a risk men should discuss with their doctor prior to starting finasteride. In some cases, sperm can be recovered from the bladder, processed in the laboratory and used to inseminate your partner (intrauterine insemination). As here reported, these observations are mainly based on self-reporting of the symptomatology by the patients and few clinical studies have been performed so far. Adverse side effects of 5-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients. .s5ap8yh1b4ZfwxvHizW3f{color:var(--newCommunityTheme-metaText);padding-top:5px}.s5ap8yh1b4ZfwxvHizW3f._19JhaP1slDQqu2XgT3vVS0{color:#ea0027} If you have retrograde ejaculation, you'll likely need treatment to get your female partner pregnant. 2020 Jan;113(1):21-50. doi: 10.1016/j.fertnstert.2019.11.030. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. I went from barely able to get an erection to having 4 very pleasurable orgasms on the third day. This report will provide you with the information you need to understand the current controversies, avoid common pitfalls, and work with your doctor to make informed choices about your prostate health. -, Baas W.R., Butcher M.J., Lwin A., Holland B., Herberts M., Clemons J., Delfino K., Althof S., Kohler T.S., McVary K.T. This site needs JavaScript to work properly. I could be wrong but none of them seem to have anhedonia or genital numbness or fatigue or insomnia or anything, just libido and ED issues. doi: 10.1210/jc.2016-2726. The common denominator in how I feel is Tribulus, period, end of sentence. ._2a172ppKObqWfRHr8eWBKV{-ms-flex-negative:0;flex-shrink:0;margin-right:8px}._39-woRduNuowN7G4JTW4I8{margin-top:12px}._136QdRzXkGKNtSQ-h1fUru{display:-ms-flexbox;display:flex;margin:8px 0;width:100%}.r51dfG6q3N-4exmkjHQg_{font-size:10px;font-weight:700;letter-spacing:.5px;line-height:12px;text-transform:uppercase;-ms-flex-pack:justify;justify-content:space-between;-ms-flex-align:center;align-items:center}.r51dfG6q3N-4exmkjHQg_,._2BnLYNBALzjH6p_ollJ-RF{display:-ms-flexbox;display:flex}._2BnLYNBALzjH6p_ollJ-RF{margin-left:auto}._1-25VxiIsZFVU88qFh-T8p{padding:0}._2nxyf8XcTi2UZsUInEAcPs._2nxyf8XcTi2UZsUInEAcPs{color:var(--newCommunityTheme-widgetColors-sidebarWidgetTextColor)} These anecdotes report success using steroids or ancillaries. Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. Keywords: Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: Imipramine, an antidepressant. I also tried testosterone treatment but it had almost no effect regardless of dosage. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron, of course he doesnt have any affliate links to those products. J Sex Med. government site. ._9ZuQyDXhFth1qKJF4KNm8{padding:12px 12px 40px}._2iNJX36LR2tMHx_unzEkVM,._1JmnMJclrTwTPpAip5U_Hm{font-size:16px;font-weight:500;line-height:20px;color:var(--newCommunityTheme-bodyText);margin-bottom:40px;padding-top:4px;text-align:left;margin-right:28px}._2iNJX36LR2tMHx_unzEkVM{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex}._2iNJX36LR2tMHx_unzEkVM ._24r4TaTKqNLBGA3VgswFrN{margin-left:6px}._306gA2lxjCHX44ssikUp3O{margin-bottom:32px}._1Omf6afKRpv3RKNCWjIyJ4{font-size:18px;font-weight:500;line-height:22px;border-bottom:2px solid var(--newCommunityTheme-line);color:var(--newCommunityTheme-bodyText);margin-bottom:8px;padding-bottom:8px}._2Ss7VGMX-UPKt9NhFRtgTz{margin-bottom:24px}._3vWu4F9B4X4Yc-Gm86-FMP{border-bottom:1px solid var(--newCommunityTheme-line);margin-bottom:8px;padding-bottom:2px}._3vWu4F9B4X4Yc-Gm86-FMP:last-of-type{border-bottom-width:0}._2qAEe8HGjtHsuKsHqNCa9u{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-bodyText);padding-bottom:8px;padding-top:8px}.c5RWd-O3CYE-XSLdTyjtI{padding:8px 0}._3whORKuQps-WQpSceAyHuF{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}._1Qk-ka6_CJz1fU3OUfeznu{margin-bottom:8px}._3ds8Wk2l32hr3hLddQshhG{font-weight:500}._1h0r6vtgOzgWtu-GNBO6Yb,._3ds8Wk2l32hr3hLddQshhG{font-size:12px;line-height:16px;color:var(--newCommunityTheme-actionIcon)}._1h0r6vtgOzgWtu-GNBO6Yb{font-weight:400}.horIoLCod23xkzt7MmTpC{font-size:12px;font-weight:400;line-height:16px;color:#ea0027}._33Iw1wpNZ-uhC05tWsB9xi{margin-top:24px}._2M7LQbQxH40ingJ9h9RslL{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px} I felt fine while taking it but it gave me gyno so I stopped. Finasteride is available as a lower-cost generic. This stuff WORKS. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? Best, Dr. Emer. Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Drugs generally won't help if retrograde ejaculation is due to surgery that causes permanent physical changes of your anatomy. If I do achieve an erection it has to be constantly stimulated or it goes away FAST and even thats not a guarantee. For details, see text. Better to learn the cause of PFS and create a cure based on that. Since your question stresses on age and since there might be other young people in their 20s and 30s who might find this question and come looking for answers, I thought I might start by pointing that out. His article with all the studies hes referencing: Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. After 4 months of no progress whatsoever I tried the regimen that saved me - at least thats the only explanation I have. Its less than ideal though when trying to help people and you get banned for it, That forum is a farce, it seems their solution is to just wait, could help for some but others are waiting for years without improving. Waitttt wait wait. 2022 Oct;11(10):1452-1457. doi: 10.21037/tau-22-92. Your doctor will ask you questions about your health and symptoms. Retrograde ejaculation - Diagnosis and treatment - Mayo Clinic What's the best treatment to use to try to get my partner pregnant? Its easy to point to a little blue pill you took 10 years ago than to look for other causes. In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. https://www.hairlosstalk.com/interact/threads/how-i-cured-my-problem-with-post-finasteride-syndrome.125634/. I'm Just 18 and I'm Losing my Hair. With constant stress, your adrenals do not get a chance for recovery. Press question mark to learn the rest of the keyboard shortcuts. 2023 by The President and Fellows of Harvard College, Do not sell my personal information | Privacy Policy. Careers. It can prevent hair loss and decrease prostate enlargement, but not surprisingly, it can also suppress sexual function. Personally, I believe its become the boogeyman for a bucket list of sexual problems. reddit 2011 Mar;8(3):872-84. doi: 10.1111/j.1743-6109.2010.02157.x. Being ready to answer your doctor's questions might save time to go over any points you want to spend more time on. Sexual side effects: Loss of libido, impotence, testicular pain, testicle shrinkage, minor Peyronies (up to 10 degrees), penis pain, watery semen, Mental: Anxiety, insomnia, cognitive issues / brain fog. Accessibility Around 8 months and i was pretty much recovered. Res. 2013 Oct;10(10):2598-603. doi: 10.1111/jsm.12269. And quite frankly, if you think big pharma doesn't have millions and millions of dollars wrapped up in trying to cover up just how severely finasteride has destroyed mens' lives, you're fooling yourself. ._1QwShihKKlyRXyQSlqYaWW{height:16px;width:16px;vertical-align:bottom}._2X6EB3ZhEeXCh1eIVA64XM{margin-left:3px}._1jNPl3YUk6zbpLWdjaJT1r{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;padding:0 4px}._1jNPl3YUk6zbpLWdjaJT1r._39BEcWjOlYi1QGcJil6-yl{padding:0}._2hSecp_zkPm_s5ddV2htoj{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;margin-left:0;padding:0 4px}._2hSecp_zkPm_s5ddV2htoj._39BEcWjOlYi1QGcJil6-yl{padding:0}._1wzhGvvafQFOWAyA157okr{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;box-sizing:border-box;line-height:14px;padding:0 4px}._3BPVpMSn5b1vb1yTQuqCRH,._1wzhGvvafQFOWAyA157okr{display:inline-block;height:16px}._3BPVpMSn5b1vb1yTQuqCRH{background-color:var(--newRedditTheme-body);border-radius:50%;margin-left:5px;text-align:center;width:16px}._2cvySYWkqJfynvXFOpNc5L{height:10px;width:10px}.aJrgrewN9C8x1Fusdx4hh{padding:2px 8px}._1wj6zoMi6hRP5YhJ8nXWXE{font-size:14px;padding:7px 12px}._2VqfzH0dZ9dIl3XWNxs42y{border-radius:20px}._2VqfzH0dZ9dIl3XWNxs42y:hover{opacity:.85}._2VqfzH0dZ9dIl3XWNxs42y:active{transform:scale(.95)} Their attitude is 100% there is no cure, it wont get better, nothing works, anything that does work doesnt work long term, and thats just how it is. ._2Gt13AX94UlLxkluAMsZqP{background-position:50%;background-repeat:no-repeat;background-size:contain;position:relative;display:inline-block} Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. Wonder if this would work for me? Depending on the likely cause of your dry orgasms and whether you need evaluation and treatment to help you get your female partner pregnant, you might need to see a urinary and reproductive specialist (urologist). Hcg I did 3000iu the first day then 250iu every other day for the four weeks. https://old.reddit.com/r/FinasterideSyndrome/comments/psjeuu/could_trying_finasteride_for_1_month_be_harmfull/he38hlf/. A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats. Authors received funding from the Post-Finasteride Foundation in order to study PFS symptomatology of patients and in experimental models. moreplatesmoredates.com. " Im talking about the physical inability to have erections and sex drive".